The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6866637 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 15, 2005

Filed:

Apr. 26, 2001
Applicants:

Steven C. George, Irvine, CA (US);

Nikolaos Tsoukias, Baltimore, MD (US);

Inventors:

Steven C. George, Irvine, CA (US);

Nikolaos Tsoukias, Baltimore, MD (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B005/00 ;
U.S. Cl.
CPC ...
Abstract

The invention provides an estimation of key flow-independent parameters characteristic of NO exchange in the lungs, namely: 1) the steady state alveolar concentration, C; 2) the maximum flux of NO from the airways, J; and 3) the diffusing capacity of NO in the airways, D. The parameters were estimated from a single exhalation maneuver comprised of a pre-expiratory breathhold, followed by an exhalation in which the flow rate progressively decreased. The mean values for J, D, and Cdo not depend on breathhold time for breathhold times greater than approximately 10 seconds.estimates of the parameter confidence intervals demonstrates that a breathhold no longer than 20 seconds may be adequate, and that Jbe can estimated with the smallest uncertainty, and Dthe largest.


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