The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2005
Filed:
Feb. 21, 2002
Applicants:
Aldo Salimbeni, Lomagna, IT;
Carlo Alberto Maggi, Pomezia, IT;
Stefano Manzini, Pomezia, IT;
Damiano Turozzi, Pomezia, IT;
Inventors:
Aldo Salimbeni, Lomagna, IT;
Carlo Alberto Maggi, Pomezia, IT;
Stefano Manzini, Pomezia, IT;
Damiano Turozzi, Pomezia, IT;
Assignees:
Menarini Richerche S.p.A., Pomezia, IT;
Berlin-Chemie AG, Berlin, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H019/073 ; C07H019/06 ; A61K031/7072 ;
U.S. Cl.
CPC ...
Abstract
Process of preparing (E)-5-(2-bromovynyl)-2'-deoxyuridine (Brivudine) characterized in that halogen-free solvent selected form esters or cyclic ethers are used in the bromination step of 5-ethyl-2′-deoxyuridine diacylate. The use of solvents is advantageous in respect of toxicity, discharge costs and environment protection.