The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2005
Filed:
Nov. 08, 2001
James Travis, Athens, GA (US);
Jan S. Potempa, Athens, GA (US);
Agnieszka Banbula, Chapel Hill, NC (US);
Marcin Bugno, Chapel Hill, NC (US);
James Travis, Athens, GA (US);
Jan S. Potempa, Athens, GA (US);
Agnieszka Banbula, Chapel Hill, NC (US);
Marcin Bugno, Chapel Hill, NC (US);
University of Georgia Research Foundation, Inc., Athens, GA (US);
Abstract
The present invention provides isolated polypeptides, dipeptidylpeptidases, active analogs, active fragments, or active modifications thereof, having amidolytic activity for cleavage of a peptide bond between the second and third amino acids from the N-terminal end of a target polypeptide, wherein the target polypeptide has an aliphatic or an aromatic residue as a substituent on the α-carbon atom of the second amino acid from the N-terminal end of the peptide. Isolated nucleic acids encoding dipeptidylpeptidases are also provided, as are methods of reducing growth of a bacterium by inhibiting a dipeptidylpeptidase.