The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2005
Filed:
Sep. 05, 2001
Fatih M. Uckun, White Bear Lake, MN (US);
Yaguo Zheng, New Brighton, MN (US);
Sutapa Ghosh, Shoreview, MN (US);
Fatih M. Uckun, White Bear Lake, MN (US);
Yaguo Zheng, New Brighton, MN (US);
Sutapa Ghosh, Shoreview, MN (US);
Parker Hughes Institute, St. Paul, MN (US);
Abstract
Novel compounds and pharmaceutical compositions useful as EGFR tyrosine kinase inhibitors. Methods of the invention include administration of the EGFR TK inhibitors to treat diseases characterized by enhanced expression of EGF, including cancers, particularly breast cancer. Additionally, a homology model representing the structure of EGFR kinase domain is provided, which model is useful for the rationally design and screening of compounds predicted to bind favorably to EGFR and to inhibit EGFR TK.