The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2005
Filed:
Aug. 05, 2002
Kah-hiing John Ling, Newport Coast, CA (US);
Wu Yang, Irvine, CA (US);
Jinsong NI, Foothill Ranch, CA (US);
Haiqing Yuan, Irvine, CA (US);
Diane D. S. Tang-liu, Newport Beach, CA (US);
Kah-Hiing John Ling, Newport Coast, CA (US);
Wu Yang, Irvine, CA (US);
Jinsong Ni, Foothill Ranch, CA (US);
Haiqing Yuan, Irvine, CA (US);
Diane D. S. Tang-Liu, Newport Beach, CA (US);
Allergan, Inc., Irvine, CA (US);
Abstract
9,11-Cycloendoperoxide derivatives of biologically active prostaglandin analogs, and particularly of the ocular hypotensive drugs Bimatoprost, Latanaprost, Unoprostone, Travoprost and prostaglandin H1-ethanolamide or of structurally closely related analogs, are pro-drugs which hydrolyze under physiological conditions to provide prostaglandin analogues that are capable of providing sustained ocular and other in vivo concentrations of the respective drugs. The compounds of the invention have the formula shown below where the variables have the meaning defined in the specification.