The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2005
Filed:
Nov. 12, 2002
Nicolas G. Bazan, New Orleans, LA (US);
Dennis Paul, New Orleans, LA (US);
Carlos Sunkel, Madrid, ES;
Julio Alvarez-builla, Madrid, ES;
Nicolas G. Bazan, New Orleans, LA (US);
Dennis Paul, New Orleans, LA (US);
Carlos Sunkel, Madrid, ES;
Julio Alvarez-Builla, Madrid, ES;
The Foundation for the LSU Health Sciences Center, New Orleans, LA (US);
Abstract
The present invention relates to pharmaceutical combinations of opioid and non-opioid analgesics in an intimate admixture with an analgesic from a series of N-acylated 4-hydroxyphenylamine derivatives, linked via an alkylene bridge to the nitrogen atom of a 1,2-benzisothiazol-3(2H)-one 1,1-dioxide group and methods for their use to alleviate pain in mammals. The analgesic combinations exhibit enhanced analgesic potency, do not suppress blood coagulation, and have little hepatotoxic effect.