The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2005

Filed:

Dec. 09, 2003
Applicants:

Terrence Joseph Connolly, Redwood City, CA (US);

Joseph Armstrong Martin, Menlo Park, CA (US);

Anthony Prince, Los Altos, CA (US);

Keshab Sarma, Sunnyvale, CA (US);

Inventors:

Terrence Joseph Connolly, Redwood City, CA (US);

Joseph Armstrong Martin, Menlo Park, CA (US);

Anthony Prince, Los Altos, CA (US);

Keshab Sarma, Sunnyvale, CA (US);

Assignee:

Roche Palo Alto LLC, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K031/7068 ; A61K031/7052 ; A61K031/70 ; C07H019/067 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to the hemisulfate salt of 1-[4(S)-azido-2(S),3(R)-dihydroxy-4-(hydroxymethyl)-1(R)-cyclopentyl]cytosine (Ia) with improved stability and physical properties which facilitate manufacturing, handling and formulating I and polymorphic crystalline forms thereof.


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