The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2005
Filed:
Oct. 21, 2003
Joseph A. Gardella, Jr., Buffalo, NY (US);
Jiaxing Chen, Angleton, TX (US);
Norma L. Hernandez DE Gatica, Lakewood, OH (US);
Joo-woon Lee, Austin, TX (US);
Joseph A. Gardella, Jr., Buffalo, NY (US);
Jiaxing Chen, Angleton, TX (US);
Norma L. Hernandez de Gatica, Lakewood, OH (US);
Joo-Woon Lee, Austin, TX (US);
Research Foundation of State University of New York at Buffalo, Amherst, NY (US);
Abstract
The present invention provides a novel method for monitoring the reaction kinetics of the biodegradable polymers, and the surface concentration of a drug in a polymer blend matrix. Detailed information on surface concentration, degradation rates, degradation kinetics and mechanism, is provided by using Time-of-Flight Secondary Ion Mass Spectrometry (ToF SIMS) measurements. Also provided is a method for determining oligomers in hydrolyzed biodegradable polymers.