The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2005
Filed:
Feb. 25, 1999
Maarten Hendrik Stuiver, Oegstgeest, NL;
Jerome Hubertus Henricus Victor Custers, Leiden, NL;
Marianne Beatrix Sela-buurlage, Kefar Bilu, IL;
Leo Sjoerd Melchers, Leiden, NL;
Wessel Lageweg, Monnickendam, NL;
Anne Silene Ponstein, Leiden, NL;
Johanna Pieternella Els Van Deventer-troost, Delft, NL;
Maarten Hendrik Stuiver, Oegstgeest, NL;
Jerome Hubertus Henricus Victor Custers, Leiden, NL;
Marianne Beatrix Sela-Buurlage, Kefar Bilu, IL;
Leo Sjoerd Melchers, Leiden, NL;
Wessel Lageweg, Monnickendam, NL;
Anne Silene Ponstein, Leiden, NL;
Johanna Pieternella Els Van Deventer-Troost, Delft, NL;
Syngenta Mogen B.V., Leiden, NL;
Abstract
The present invention provides an isolated protein obtainable from a plant source which has antifungal activity, specifically anti-Phytophthora activity and/or anti-Pythium activity and a molecular weight of about 55-65 kDa as judged by SDS PAGE-electrophoresis, an isolated DNA sequence comprising an open reading frame capable of encoding a protein according to the invention, preferably characterized in that it comprises an open reading frame which is capable of encoding a protein depicted in SEQ ID NO. 16, SEQ ID NO. 57, SEQ ID NO. 70, SEQ ID NO. 72 or SEQ ID NO. 74 or muteins thereof, and DNA capable of hybridizing therewith under stringent conditions. The invention further comprises plants incorporating chimeric DNA capable of encoding a protein according to the invention, and wherein the protein is expressed. Also shown is the carbohydrate and preferably hexose oxidating activity of said protein. Also methods are provided for combating fungi, especially Phytophthora and Pythium species, using a protein or a host cell capable of producing the protein.