The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2005

Filed:

Jun. 22, 2001
Applicants:

Yoshihiko Makino, Saitama, JP;

Yoshihiko Abe, Saitama, JP;

Masashi Ogawa, Tokyo, JP;

Makoto Takagi, Fukuoka, JP;

Shigeori Takenaka, Fukuoka, JP;

Kenichi Yamashita, Fukuoka, JP;

Inventors:

Yoshihiko Makino, Saitama, JP;

Yoshihiko Abe, Saitama, JP;

Masashi Ogawa, Tokyo, JP;

Makoto Takagi, Fukuoka, JP;

Shigeori Takenaka, Fukuoka, JP;

Kenichi Yamashita, Fukuoka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q001/68 ; C12P019/34 ; B01D057/02 ; G01N030/02 ;
U.S. Cl.
CPC ...
Abstract

A method of detecting nucleic acid fragments in plural samples is performed by the steps of: attaching an electroconductive label to nucleic acid fragments in one sample and attaching a different electroconductive label to nucleic acid fragments in another sample; preparing a mixture of these samples; spotting the mixture on an electroconductive microarray having plural electrodes onto which probe molecules complementary to the nucleic acid fragments are fixed, so that hybridization between the nucleic acid fragments and the probe molecules on the electroconductive microarray can proceed to form hybrid structures; applying to the electrode an electric potential corresponding to the oxidation-reduction potential of the former label and detecting on the electrode an electric current; applying to the electrode an electric potential corresponding to the oxidation-reduction potential of the latter label and detecting on the electrode an electric current; and comparing the electric current detected in the former detecting procedure and that detected in the latter detecting procedure.


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