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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6863885 B1

PDFFull Text
Expired
Date of Patent:
Mar. 08, 2005

Filed:

Jul. 22, 2002

Method of decreasing radiation or radio-mimetic chemotherapy for hematopoietic pluripotent cell engraftment

Applicants:

Michael Mardiney, Iii, Baltimore, MD (US);

Harry L. Malech, Bethesda, MD (US);

Inventors:

Michael Mardiney, III, Baltimore, MD (US);

Harry L. Malech, Bethesda, MD (US);

Assignee:

The United States of America as represented by the Department of Health and Human Servies, Washington, DC (US);

Attorney:

Needle & Rosenberg, P.C.

Primary Examiner:

Q Janice Li

Int. Cl.
CPC ...
A01N065/00 ; C12P021/02 ; C12N005/0008 ; A61K038/00 ; A61M005/00 ;
U.S. Cl.
CPC ...
Abstract

The present invention provides a method of engrafting donor mammalian hematopoietic pluripotent cells in a mammalian recipient using a decreased amount of radiation, comprising: (a) administering to the recipient at least one dosage of a hematopoietic growth factor; (b) subjecting the recipient to a low dosage of radiation; and (c) transplanting the donor hematopoietic pluripotent cells in the recipient, thereby engrafting the donor mammalian hematopoietic pluripotent cells in the mammalian recipient using a decreased amount of radiation. The invention also provides a method of engrafting donor mammalian hematopoietic pluripotent cells in a mammalian recipient using a decreased amount of radiomimetic compound, comprising: (a) administering to the recipient at least one dosage of a hematopoietic growth factor; (b) subjecting the recipient to a low dosage of radiomimetic compound; and (c) transplanting the donor hematopoietic pluripotent cells in the recipient, thereby engrafting the donor mammalian hematopoietic pluripotent cells in the mammalian recipient using a decreased amount of radiomimetic compound.

Find Patent Forward Citations

Mardiney, III, Michael. (2005). Method of decreasing radiation or radio-mimetic chemotherapy for hematopoietic pluripotent cell engraftment (U.S. Patent No. 6863885). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6863885

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