The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2005

Filed:

Dec. 17, 2002
Applicants:

Seiji Yamada, Kurashiki, JP;

Ken Ishihara, Kurashiki, JP;

Toshio Nakamatsu, Kurashiki, JP;

Inventors:

Seiji Yamada, Kurashiki, JP;

Ken Ishihara, Kurashiki, JP;

Toshio Nakamatsu, Kurashiki, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C255/50 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to a production method of 4'-bromomethyl-2-cyanobiphenyl, which includes reacting 4′-methyl-2-cyanobiphenyl with bromine in the presence of a radical initiator and an oxidant. According to the present invention, since bromine can be regenerated by reacting hydrogen bromide, which is by-produced with the progress of bromination, with an oxidant, inhibition of bromination by hydrogen bromide, coloring by bromine and the like can be prevented. Thus, 4′-bromomethyl-2-cyanobiphenyl useful as a starting material of pharmaceutical products can be produced industrially beneficially.


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