The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 22, 2005

Filed:

Apr. 30, 2002
Applicants:

Tadashi Araki, Chiba, JP;

Ichirou Ikeda, Chiba, JP;

Kaori Matoishi, Chiba, JP;

Reiko Abe, Chiba, JP;

Toshihiro Oikawa, Chiba, JP;

Yasuko Matsuba, Fukuoka, JP;

Hiroki Ishibashi, Fukuoka, JP;

Kiyoteru Nagahara, Fukuoka, JP;

Yasushi Fukuiri, Fukuoka, JP;

Inventors:

Tadashi Araki, Chiba, JP;

Ichirou Ikeda, Chiba, JP;

Kaori Matoishi, Chiba, JP;

Reiko Abe, Chiba, JP;

Toshihiro Oikawa, Chiba, JP;

Yasuko Matsuba, Fukuoka, JP;

Hiroki Ishibashi, Fukuoka, JP;

Kiyoteru Nagahara, Fukuoka, JP;

Yasushi Fukuiri, Fukuoka, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H021/00 ; C07H021/02 ; C07H021/04 ;
U.S. Cl.
CPC ...
Abstract

The invention provides a method for producing a cytosine nucleoside compound from pentose-1-phosphate and cytosine or a derivative thereof using a nucleoside phosphorylase reactive to cytosine or a bacterium having the enzyme activity. The invention also provides a method for specifically reducing an activity to degrade the substrates or the product, resulting in efficient production of the cytosine nucleoside compound. According to the invention, little by-product is produced in producing cytonucleocide compounds.


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