The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2005
Filed:
Apr. 04, 2002
Gerald Juergen Roth, Biberach, DE;
Armin Heckel, Biberach, DE;
Thorsten Lehmann-lintz, Ochsenhausen, DE;
Joerg Kley, Mittelbiberach, DE;
Frank Hilberg, Vienna, AT;
Jacobus Van Meel, Moedling, AT;
Gerald Juergen Roth, Biberach, DE;
Armin Heckel, Biberach, DE;
Thorsten Lehmann-Lintz, Ochsenhausen, DE;
Joerg Kley, Mittelbiberach, DE;
Frank Hilberg, Vienna, AT;
Jacobus Van Meel, Moedling, AT;
Boehringer Ingelheim Pharma KG, Ingelheim, DE;
Abstract
The present invention relates to indolinones substituted in the 6-position of general formulawhereinRto Rand X are defined as in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof which have valuable pharmacological properties, in particular an inhibiting effect on various receptor tyrosine kinases and cyclin/CDK complexes and on the proliferation of endothelial cells and various, pharmaceutical compositions containing these compounds, their use and processes for preparing them.