The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2005
Filed:
Aug. 21, 2000
Malcolm F. G. Stevens, Leicestershire, GB;
Andrew D. Westwell, Nottingham, GB;
Mei-sze Chua, Singapore, SG;
Tracey D. Poole, Chesterfield, GB;
Ian P. Hutchinson, Nottingham, GB;
Malcolm F. G. Stevens, Leicestershire, GB;
Andrew D. Westwell, Nottingham, GB;
Mei-Sze Chua, Singapore, SG;
Tracey D. Poole, Chesterfield, GB;
Ian P. Hutchinson, Nottingham, GB;
Cancer Research Technology Limited, London, GB;
Abstract
Substituted 2-phenylbenzazole compounds of formula (I) wherein X represents S or O and Q represents a direct bond, —CH2— or —CH═Ch—, exhibt selective antiproliferactive activity in respect of mammalian tumour cells. At least in preferred enbodiments the benzene ring of the benzazole nucleus has a halogen substituent, preferably flourine, and the 2-phenyl group has a 4'-amino substituent which may be conjugated with an amino acid to provide a water soluble amino acid amide prodrug or salt thereof.