The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2005
Filed:
Apr. 28, 2003
Jose Repolles Moliner, Barcelona, ES;
Francisco Pubill Coy, Barcelona, ES;
Lydia Cabeza Llorente, Barcelona, ES;
Marcel.li Carbo Banus, Barcelona, ES;
Cristina Negrie Rofes, Leiden, NL;
Juan Antonio Cerda Riudavets, Barcelona, ES;
Alicia Ferrer Siso, Barcelona, ES;
Marek W. Radomski, Edmonton, CA;
Eduardo Perez-rasilla, Barcelona, ES;
Juan Martinez Bonnin, Barcelona, ES;
Jose Repolles Moliner, Barcelona, ES;
Francisco Pubill Coy, Barcelona, ES;
Lydia Cabeza Llorente, Barcelona, ES;
Marcel.li Carbo Banus, Barcelona, ES;
Cristina Negrie Rofes, Leiden, NL;
Juan Antonio Cerda Riudavets, Barcelona, ES;
Alicia Ferrer Siso, Barcelona, ES;
Marek W. Radomski, Edmonton, CA;
Eduardo Perez-Rasilla, Barcelona, ES;
Juan Martinez Bonnin, Barcelona, ES;
Lacer, S.A., Barcelona, ES;
Abstract
Novel derivatives of isosorbide mononitrate and its pharmaceutically acceptable salts, which have vasodilating activity with a reduced effect of tolerance, of the general formula (I)in which A and B independently represent any of the groups—ONOand —Z—CO—R, wherein Z is an oxygen atom or sulphur atom and R is an alkyl C-Cgroup, an aryl group or an aralkyl group, eventually substituted, or the groupin which Ris hydrogen, or an alkyl C-Cgroup, an aryl group or an aralkyl group, eventually substituted, with the proviso that one of A or B is always —ONO, but never both of them at the same time, when Z is an sulphur atom R is an alkyl C-Cgroup, an aryl group or an aralkyl group, eventually substituted, and when Z is an oxygen atom R is the group