The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 22, 2005

Filed:

Dec. 27, 2001
Applicants:

Hidemitsu Nishida, Tokyo, JP;

Fumihiko Saitoh, Tokyo, JP;

Kousuke Harada, Shizuoka, JP;

Ikuya Shiromizu, Tokyo, JP;

Takafumi Mukaihira, Tokyo, JP;

Inventors:

Hidemitsu Nishida, Tokyo, JP;

Fumihiko Saitoh, Tokyo, JP;

Kousuke Harada, Shizuoka, JP;

Ikuya Shiromizu, Tokyo, JP;

Takafumi Mukaihira, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K031/33 ; A61K031/495 ; C07D241/00 ; C07D491/00 ; C07D243/00 ;
U.S. Cl.
CPC ...
Abstract

This invention relates to tricyclic compounds having spiro union represented by the following formula (I) or its salt which is useful as a drug, and in particular, as an inhibitor for activated blood coagulation factor X, which can be administered orally and which exhibits strong anticoagulation action. The invention also relates to a pharmacophore which was derived from the compound and is useful in molecular designing of the FXa inhibitor.


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