The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2005
Filed:
Mar. 31, 2003
Suman Preet Singh Khanuja, Lucknow, IN;
Jai Shanker Arya, Lucknow, IN;
Ranganathan Santha Kumar Tiruppadiripuliyur, Lucknow, IN;
Dharmendra Saikia, Lucknow, IN;
Harpreet Kaur, Lucknow, IN;
Monika Singh, Lucknow, IN;
Subhash Chandra Gupta, Lucknow, IN;
Ajit Kumar Shasany, Lucknow, IN;
Mahendra Pandurang Darokar, Lucknow, IN;
Santosh Kumar Srivastava, Lucknow, IN;
Madan Mohan Gupta, Lucknow, IN;
Subash Chandra Verma, Lucknow, IN;
Anirban Pal, Lucknow, IN;
Suman Preet Singh Khanuja, Lucknow, IN;
Jai Shanker Arya, Lucknow, IN;
Ranganathan Santha Kumar Tiruppadiripuliyur, Lucknow, IN;
Dharmendra Saikia, Lucknow, IN;
Harpreet Kaur, Lucknow, IN;
Monika Singh, Lucknow, IN;
Subhash Chandra Gupta, Lucknow, IN;
Ajit Kumar Shasany, Lucknow, IN;
Mahendra Pandurang Darokar, Lucknow, IN;
Santosh Kumar Srivastava, Lucknow, IN;
Madan Mohan Gupta, Lucknow, IN;
Subash Chandra Verma, Lucknow, IN;
Anirban Pal, Lucknow, IN;
Council of Scientific and Industrial Research, New Delhi, IN;
Abstract
The present invention relates to a novel nitrile glycoside of Formula I named NIAZIRIDIN and to analogues and derivatives thereof. The present invention also relates to a process for the isolation of a novel nitrile glycoside of Formula I below named NIAZIRIDIN and its derivatives and analogues by bioactivity-guided fractionation from the pods ofThe present invention particularly relates to the bioenhancing activity of the novel nitrile glycoside of Formula I below named NIAZIRIDIN and its derivatives and analogues in enhancing bioactivity of commonly used antibiotics such as rifampicin, tetracycline and ampicillin against Gram (+) and (−) bacteria. The biomolecule also enhances the absorption of drugs, vitamins and nutrients through the gastro-intestinal membrane increasing their bio-availability. Therefore niaziridin can be used in combination therapy with drugs and nutrients resulting in reduced drug associated toxicity, reduced cost and duration of chemotherapy.