The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2005
Filed:
Jun. 07, 1995
Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
Robert C. Thompson, Boulder, CO (US);
Charles H. Hannum, Sunnyvale, CA (US);
Stephen P. Eisenberg, Boulder, CO (US);
William P. Arend, Denver, CO (US);
Fenneke G. Joslin, Denver, CO (US);
Andreas Sommer, Danville, CA (US);
Robert C. Thompson, Boulder, CO (US);
Charles H. Hannum, Sunnyvale, CA (US);
Stephen P. Eisenberg, Boulder, CO (US);
William P. Arend, Denver, CO (US);
Fenneke G. Joslin, Denver, CO (US);
Andreas Sommer, Danville, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
The Regents of the University of Colorado, Boulder, CO (US);
Abstract
Compounds are disclosed having the general formula R—X—R, wherein Rand Rare biologically active groups, at least one of which is polypeptidic. X is a non-peptidic polymeric group. Rand Rmay be the same or different. Preferred Rand Rgroups are interleukin-1 receptor antagonist, 30 kDa TNF inhibitor, interleukin-2 receptors and CR1 and muteins thereof. Also included are site selectively modified interleukin-1 receptor antagonist and 30 kDa TNF inhibitor.