The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 22, 2005

Filed:

Jun. 20, 2003
Applicants:

Gary W. Blissard, Ithaca, NY (US);

Jodie T. Mangor, Ithaca, NY (US);

Scott A. Monsma, Madison, WI (US);

Inventors:

Gary W. Blissard, Ithaca, NY (US);

Jodie T. Mangor, Ithaca, NY (US);

Scott A. Monsma, Madison, WI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K048/00 ; C12N015/866 ; C12N015/63 ;
U.S. Cl.
CPC ...
Abstract

A pseudotyped baculovirus comprises a deletion, inactivation or reduction from regulation of a baculovirus envelope protein gene, and is engineered to express an envelope protein from another virus or cell, or another protein or molecule that facilitates entry of the baculovirus into a non-host cell, or provided with a heterologous envelope protein or another protein or molecule that facilitates entry of the baculovirus into a non-host cell by other suitable means. Such baculoviruses can be used to efficiently deliver genes to mammalian cells or organisms, and such genes can be expressed either from the baculovirus genome, or integrated into the mammalian cell genome, and can be used for expression of proteins such that purification of secreted or other protein products does not require removal of contaminating baculovirus particles or baculovirus envelope proteins.


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