The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2005
Filed:
Nov. 15, 2002
Methods of modulating serine/threonine protein kinase function with azabenzimidazole-based compounds
Gerald Mcmahon, San Francisco, CA (US);
Heinz Weinberger, Sulzbach/Ts, DE;
Bernhard Kutscher, Maintal, DE;
Harald App, San Francisco, CA (US);
Gerald McMahon, San Francisco, CA (US);
Heinz Weinberger, Sulzbach/Ts, DE;
Bernhard Kutscher, Maintal, DE;
Harald App, San Francisco, CA (US);
Zentaris GmbH, Frankfurt/Main, DE;
Abstract
The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with azabenzimidazole-based compounds. The methods incorporate cells that express a serine/threonine protein kinase, such as RAF. In addition, the invention describes methods of preventing and treating serine/threonine protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to azabenzimidazole compounds and pharmaceutical compositions comprising these compounds.