The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2005

Filed:

Mar. 10, 2000
Applicants:

Edward N. Hill, Wilmington, NC (US);

Thomas W. Leonard, Wilmington, NC (US);

Frederick D. Sancilio, Wilmington, NC (US);

Katherin M. Schlipp, Wilmington, NC (US);

Dean G. Shirazi, Wilmington, NC (US);

Robert R. Whittle, Wilmington, NC (US);

Inventors:

Edward N. Hill, Wilmington, NC (US);

Thomas W. Leonard, Wilmington, NC (US);

Frederick D. Sancilio, Wilmington, NC (US);

Katherin M. Schlipp, Wilmington, NC (US);

Dean G. Shirazi, Wilmington, NC (US);

Robert R. Whittle, Wilmington, NC (US);

Assignee:

Endeavor Pharmaceuticals, Wilmington, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/56 ;
U.S. Cl.
CPC ...
Abstract

A composition of matter is provided having a mixture of active estrogenic compounds. The mixture is present in chemically pure form. The mixture includes salts of conjugated estrone, conjugated equilin, conjugated Δ-dehydroestrone, conjugated 17α-estradiol, conjugated 17α-dihydroequilin, conjugated 17β-dihydroequilin, conjugated 17β-estradiol, conjugated equilenin, conjugated 17α-dihydroequilenin, and conjugated 17β-dihydroequilenin. The mixture also contains the same essential estrogenic compounds present in naturally derived equine conjugated estrogens. Drug products including the composition of matter are also provided, as are methods of using these drug products to treat mammals in need of treatment. Methods of analyzing mixtures containing conjugated estrogens are also provided.


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