The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2005

Filed:

Mar. 22, 2002
Applicants:

Edward H. Ruediger, Greenfield Park, CA;

Mark G. Saulnier, Higganum, CT (US);

Francis Beaulieu, Laprairie, CA;

Carol Bachand, Candiac, CA;

Neelakantan Balusubramanian, Madison, CT (US);

Byron Hepler Long, Doylestown, PA (US);

David B. Frennesson, Naugatuck, CT (US);

Kurt Zimmermann, Durham, CT (US);

B. Narasimhulu Naidu, Durham, CT (US);

Karen Stoffan, Hartford, CT (US);

Denis Robert St. Laurent, Newington, CT (US);

Inventors:

Edward H. Ruediger, Greenfield Park, CA;

Mark G. Saulnier, Higganum, CT (US);

Francis Beaulieu, Laprairie, CA;

Carol Bachand, Candiac, CA;

Neelakantan Balusubramanian, Madison, CT (US);

Byron Hepler Long, Doylestown, PA (US);

David B. Frennesson, Naugatuck, CT (US);

Kurt Zimmermann, Durham, CT (US);

B. Narasimhulu Naidu, Durham, CT (US);

Karen Stoffan, Hartford, CT (US);

Denis Robert St. Laurent, Newington, CT (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N043/04 ; A61K031/70 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to fluoro sugar and other sugar derivatives of indolopyrrolocarbazoles, their salts and hydrates, which exhibit selective topoisomerase I (topo I) activity, are useful in inhibiting the proliferation of tumor cells and exhibit an antitumor effect, as well as processes for their preparation.


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