The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2005

Filed:

Sep. 16, 1997
Applicants:

Barbara Papadopoulu, Quebec, CA;

Marc Ouellette, Quebec, CA;

Martin Olivier, Quebec, CA;

Inventors:

Barbara Papadopoulu, Quebec, CA;

Marc Ouellette, Quebec, CA;

Martin Olivier, Quebec, CA;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N001/10 ; C12N001/11 ;
U.S. Cl.
CPC ...
Abstract

Strains of Leishmania and other macrophage-infecting parasites are provided which express the GM-CSF gene which are useful in treating hosts infected by the parasite and in protecting hosts against disease caused by infection of hosts by parasites. The parasites are reduced in their ability to infect or survive in macrophages and hence are attenuated. At least one gene of the parasite contributing to the virulence thereto may be functionally disabled. The attenuated strains may be used for administration to a host (a) to treat a host infected by Leishmania or (b) to confer protection against disease caused by a virulent Leishmania strain, or as a diagnostic reagent.


Find Patent Forward Citations

Papadopoulu, Barbara. (2005). Macrophage-infecting parasites expressing a granulocyte macrophage colony stimulated factor (U.S. Patent No. 6855537). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6855537

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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