The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2005
Filed:
Aug. 05, 2002
Jayasree Vasudevan, Anaheim, CA (US);
Alan T. Johnson, San Diego, CA (US);
Liming Wang, Irvine, CA (US);
Dehua Huang, San Diego, CA (US);
Roshantha A. Chandraratna, Laguna Hills, CA (US);
Jayasree Vasudevan, Anaheim, CA (US);
Alan T. Johnson, San Diego, CA (US);
Liming Wang, Irvine, CA (US);
Dehua Huang, San Diego, CA (US);
Roshantha A. Chandraratna, Laguna Hills, CA (US);
Allergan, Inc., Irvine, CA (US);
Abstract
A method of identifying a compound which is an inhibitor of the enzyme cytochrome P450RAI is performed by selecting a compound that has retinoid activity in an art recognized assay and includes a benzoic acid, benzoic acid ester, naphthoic acid ester or heteroaryl carboxylic acid or ester moiety, with a partial structure of —A(R)—(CH)where n is 0 and the remaining variables are as described in the specification and claims. Thereafter, a compound having the cytochrome P450RAI inhibitory activity is identified and selected where the compound has the —A(R)—(CH)—COORpartial structure wherein the variable n is 1 or 2.