The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2005
Filed:
Apr. 12, 2001
Applicants:
Seshi R. Sompuram, Brighton, MA (US);
Halasya Ramanathan, Worcester, MA (US);
Inventors:
Seshi R. Sompuram, Brighton, MA (US);
Halasya Ramanathan, Worcester, MA (US);
Assignee:
Medical Discovery Partners LLC, Sharon, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q001/00 ;
U.S. Cl.
CPC ...
Abstract
The invention describes a method for attaching biological molecules, such as proteins, nucleic acids, and carbohydrates to a glass surface. In particular, a covalent attachment method is described wherein a glass surface is first activated with a water-stable form of an isocyanate, termed a protected isocyanate. The protecting group of the isocyanate moiety is displaced by amines, hydroxyl, or carboxyl groups of biological molecules, leading to covalent attachment to the glass surface.