The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 08, 2005

Filed:

Mar. 21, 2001
Applicants:

Charles Q. Meng, Alpharetta, GA (US);

Lee K. Hoong, Suwanee, GA (US);

Patricia K. Somers, Fort Collins, CO (US);

Inventors:

Charles Q. Meng, Alpharetta, GA (US);

Lee K. Hoong, Suwanee, GA (US);

Patricia K. Somers, Fort Collins, CO (US);

Assignee:

Atherogenics, Inc., Alpharetta, GA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C309/00 ;
U.S. Cl.
CPC ...
Abstract

Thioketals and thioethers are provided that inhibit the expression of VCAM-1, and which can be used in the treatment of VCAM-1 mediated diseases including inflammatory disorders, cardiovascular diseases, occular diseases, autoimmune diseases, neurological disorders, and cancer. The compounds also can be used to treat hyperlipidemia and/or hypercholesterolemia.


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