The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2005
Filed:
Aug. 21, 2001
Takashi Deguchi, Kobe, JP;
Ryotaro Shiratake, Osaka, JP;
Fuminori Sato, Kobe, JP;
Buichi Fujitani, Sakai, JP;
Yayoi Honda, Ibaraki, JP;
Akihiko Kiyoshi, Kobe, JP;
Mitsue Notake, Suita, JP;
Graham Andrew Showell, Lackford, GB;
Robert George Boyle, Cambridge, GB;
Sukhbinder Singh Klair, Linton, GB;
Takashi Deguchi, Kobe, JP;
Ryotaro Shiratake, Osaka, JP;
Fuminori Sato, Kobe, JP;
Buichi Fujitani, Sakai, JP;
Yayoi Honda, Ibaraki, JP;
Akihiko Kiyoshi, Kobe, JP;
Mitsue Notake, Suita, JP;
Graham Andrew Showell, Lackford, GB;
Robert George Boyle, Cambridge, GB;
Sukhbinder Singh Klair, Linton, GB;
Dainippon Pharmaceutical Co., Ltd., Osaka-Fu, JP;
Abstract
Novel pyrrolidine derivatives, being useful as chymase inhibitor or intermediate for synthesis of the active compounds, which has the formula (I): wherein Ris cycloalkyl, substituted or unsubstituted phenyl or naphthyl, indanyl, thienyl, furyl, substituted or unsubstituted indolyl, benzofuryl, substituted or unsubstituted benzothienyl, etc.; Ris H, alkyl, phenyl-lower alkyl, cycloalkyl or cycloalkyl-lower alkyl; Ris (i) substituted or unsubstituted monocyclic heterocyclic group, (ii) substituted or unsubstituted benzene- or pyridine-fused heterocyclic group, or (iii) a group (a): Rand Rare independently H or OH, but Rand Rare not simultaneously H, or both form oxo; n is 0, 1, 2 or 3; or a salt thereof.