The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2005
Filed:
Dec. 15, 2000
Philippe R. Bovy, Mareil Marly, BE;
Roberto Cecchi, Lodi, IT;
Olivier Venier, Saint Mande, FR;
Sanofi-Synthelabo, Paris, FR;
Abstract
The invention concerns phenoxypropanolamines of formula (I)in which Rrepresents a hydrogen, a group —S(O)—(C-C)alk-R', (R′ being H, phenyl or (C-C)alkoxy), —NHSO—(C-C)alk or NHCO(C-C)alk; m and n are each independently 0, 1 or 2; Rand Rindependently represent a hydrogen, a (C-C)alkyl, (C-C)cycloalkyl, (C-C)alkoxy, hydrogen(C-C)alkoxy-(C-C)alkyl, mono- or di(C-C)alkamino(C-C)alkyl, pyrrolidino(C-C)alkyl, phenylamino or (C-C)alkenyl group, an aromatic or heteroaromatic group optionally substituted with a group R, an aralkyl or heteroaralkyl group optionally substituted with a group R, Rand Rcan also together constitute a saturated or unsaturated ring of 3 to 8 atoms possibly bearing a (C-C)alkyl, amino (C-C)alkyl, carbamoyl or benzyl substituent; Rrepresents a hydrogen or a halogen, or a group —CO(C-C)alk or a group —NHSO—(C-C)alk; a group (C-C)alk, a group (C-C)alkoxy, a halogen, —COOH, —COO(C-C)alk, —CN, —CONRR, —NO, —SONHor —NHSO(C-C)alk; z is 1 or 2; and the salts or solvates thereof. The compounds have agonist activity toward β-3 adrenergic receptors.