The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2005
Filed:
May. 01, 2001
Yasuo Yamamoto, Yokohama, JP;
Kenzo Hariyama, Yokohama, JP;
Yumiko Yanagisawa, Yokohama, JP;
Sojiro Shiokawa, Yokohama, JP;
Takumi Takeyasu, Hino, JP;
Osami Takenouchi, Hino, JP;
Hidenori Kasai, Hino, JP;
Yasuo Yamamoto, Yokohama, JP;
Kenzo Hariyama, Yokohama, JP;
Yumiko Yanagisawa, Yokohama, JP;
Sojiro Shiokawa, Yokohama, JP;
Takumi Takeyasu, Hino, JP;
Osami Takenouchi, Hino, JP;
Hidenori Kasai, Hino, JP;
Meiji Seika Kaisha, Ltd., Tokyo, JP;
Abstract
According to this invention, there is provided an indole derivative having the general formula (I)wherein A is an oxygen atom or a nitrogen atom which nitrogen atom is optionally substituted with an alkyl group, and (i) Rand Reach stand for a hydrogen atom or an alkyl group, independently, or (ii) Rand Ras taken together form a cycloalkyl group or an aromatic ring, or (iii) Rand Ras taken together form a heterocyclic ring, and Ris a hydrogen atom, a (C-C)alkyl group or others, Ris a substituted alkyl group and Ris a hydrogen atom, a halogen atom, an alkyl group or an alkoxy group and so on, as novel compounds by a novel chemical synthetic process. The indole derivative of formula (I) exhibits a useful chymase inhibitory activity.