The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 08, 2005

Filed:

Jan. 31, 2003
Applicants:

Robert Greenhouse, Newark, CA (US);

Saul Jaime-figueroa, Fremont, CA (US);

Lubica Raptova, Sunnyvale, CA (US);

Inventors:

Robert Greenhouse, Newark, CA (US);

Saul Jaime-Figueroa, Fremont, CA (US);

Lubica Raptova, Sunnyvale, CA (US);

Assignee:

Syntex LLC, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D403/06 ; A61K031/4178 ; A61K031/506 ; A61P011/02 ; A61P013/02 ;
U.S. Cl.
CPC ...
Abstract

This invention relates to compounds which are alpha-1 receptor agonists, preferably alpha-1A/L receptor agonists, and which are represented by Formula I:wherein X is —S(O)— or —C(O)—, A is Calkyl, aryl, heteroaryl, hydroxyalkyl, or —(CH)—NRR, and the other substituents are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, methods for their use as therapeutic agents, and methods of preparation thereof.


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