The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2005
Filed:
Apr. 12, 2001
Applicants:
Daniel P. Silver, Wayland, MA (US);
David M. Livingston, Brookline, MA (US);
Inventors:
Daniel P. Silver, Wayland, MA (US);
David M. Livingston, Brookline, MA (US);
Assignee:
Dana Farber Cancer Institute, Inc., Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N015/85 ; C12N015/63 ; A61K048/00 ; A01K067/00 ;
U.S. Cl.
CPC ...
Abstract
Nucleic acid molecules comprising at least a first signal site and a recombinase gene operably linked to an expression control sequence, such that upon entry into a cell, there is a first signal site and a second signal site positioned to mediate excision of a sufficient portion of either the recombinase gene or the expression control sequence to extinguish recombinase activity when the first and second signal sites are contacted with a recombinase, cells, transgenics and uses of the foregoing.