The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 08, 2005

Filed:

Jun. 29, 2001
Applicants:

Robert D. Bremel, Hillpoint, WI (US);

Linda U. Miller, Lodi, WI (US);

Gregory T. Bleck, Baraboo, WI (US);

Inventors:

Robert D. Bremel, Hillpoint, WI (US);

Linda U. Miller, Lodi, WI (US);

Gregory T. Bleck, Baraboo, WI (US);

Assignee:

Gala Design Inc, Middleton, WI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N015/09 ; C12N005/10 ; C12N015/63 ; C12N015/867 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to the production of proteins in host cells, and, more particularly to host cells containing multiple integrated copies of an integrating vector. Suitable integrating vectors for use in the present invention include retrovirus vectors, lentivirus vectors, transposon vectors, and adeno-associated virus vectors. Methods are provided in which the host cells are prepared by using the integrating vectors at a high multiplicity of infection. The host cells are useful for producing pharmaceutical proteins, variants of proteins for use in screening assays, and for direct use in high throughput screening.


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