The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2005
Filed:
Jul. 31, 1998
Applicants:
Christoph Von Eichel-streiber, Schweppenhausen, DE;
Patrice Boquet, Nice, FR;
Monica Thelestam, Soina, SE;
Inventors:
Christoph Von Eichel-Streiber, Schweppenhausen, DE;
Patrice Boquet, Nice, FR;
Monica Thelestam, Soina, SE;
Assignee:
Zentaris AG, Frankfurt, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 100 ; C12P 2108 ;
U.S. Cl.
CPC ...
Abstract
A method of treating a disorder characterized by an activating mutation in a Ras proto-oncogene, comprising contacting cells of a patient suffering from the disorder with a protein having the toxic activity oftoxin LT under conditions favoring inactivation of Ras by glucosylation of Ras' threonine 35 in said cell. The protein preferably is an immunotoxin that contains as a toxic domain the catalytic domain of toxin LT.