The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6849646 B1

PDF
Full Text
Expired
Date of Patent:
Feb. 01, 2005

Filed:

Oct. 14, 1999
Applicants:

Claus Fittschen, Fränkisch-Crumbach, DE;

Simon Goodman, Darmstadt, DE;

Joachim März, Gross-Gerau, DE;

Peter Raddatz, Alsbach, DE;

Matthias Wiesner, Mainz, DE;

Inventors:

Claus Fittschen, Fränkisch-Crumbach, DE;

Simon Goodman, Darmstadt, DE;

Joachim März, Gross-Gerau, DE;

Peter Raddatz, Alsbach, DE;

Matthias Wiesner, Mainz, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3144 ; A61K 31415 ; A61K 3135 ; C07D23366 ; C07D42100 ;
U.S. Cl.
CPC ...
Abstract

The invention relates to compounds having formula (I), wherein R, R, R, R, R, R, R, R, Z, m and n have the meaning cited in claim 1, and to the physiologically acceptable salts and solvates which can be used as integrin inhibitors, especially in the prophylaxis and treatment of circulatory diseases, in case of thrombosis, myocardial infarction, coronary heart diseases, arteriosclerosis, osteoporosis, pathologic processes caused or propagated by angiogenesis and in tumor therapy.


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