The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 01, 2005

Filed:

Dec. 08, 2000
Applicants:

Celia Dominguez, Thousand Oaks, CA (US);

Guoqing Chen, Thousand Oaks, CA (US);

Ning Xi, Thousand Oaks, CA (US);

Shimin Xu, Moorpark, CA (US);

Nianhe Han, Thousand Oaks, CA (US);

Qingyian Liu, Thousand Oaks, CA (US);

Qi Huang, Moorpark, CA (US);

Aaron Siegmund, Ventura, CA (US);

Michael Handley, Ventura, CA (US);

Longbin Liu, Thousand Oaks, CA (US);

Alexander Kiselyov, New York, NY (US);

Inventors:

Celia Dominguez, Thousand Oaks, CA (US);

Guoqing Chen, Thousand Oaks, CA (US);

Ning Xi, Thousand Oaks, CA (US);

Shimin Xu, Moorpark, CA (US);

Nianhe Han, Thousand Oaks, CA (US);

Qingyian Liu, Thousand Oaks, CA (US);

Qi Huang, Moorpark, CA (US);

Aaron Siegmund, Ventura, CA (US);

Michael Handley, Ventura, CA (US);

Longbin Liu, Thousand Oaks, CA (US);

Alexander Kiselyov, New York, NY (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D40112 ; C07D40312 ; A61K 314025 ;
U.S. Cl.
CPC ...
Abstract

The invention comprises novel compounds that are effective in the prophylaxis and treatment of diseases, such as integrin receptors mediated diseases, in particular, diseases or conditions mediated by integrin receptors, such as a αβ, αβ, αβ, αβand the like. The invention encompasses novel compounds, pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of such diseases and disorders. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.


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