The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2005
Filed:
Feb. 08, 2002
Dan Gazit, Jerusalem, IL;
Yoram Zilberman, Jerusalem, IL;
Gadi Turgeman, Jerusalem, IL;
Gadi Pelled, Rishon Leziyon, IL;
Gerhard Gross, Braunschweig, DE;
Stefan Czichos, Peine, DE;
Andrea Hoffmann, Hannover, DE;
Dan Gazit, Jerusalem, IL;
Yoram Zilberman, Jerusalem, IL;
Gadi Turgeman, Jerusalem, IL;
Gadi Pelled, Rishon Leziyon, IL;
Gerhard Gross, Braunschweig, DE;
Stefan Czichos, Peine, DE;
Andrea Hoffmann, Hannover, DE;
Yissum Research Development Company of the Hebrew University of Jerusalem, Jerusalem, IL;
Gesellschaft Fuer Biotechnologische Forschung MBH, Braunschweig, DE;
Abstract
The invention relates to methods of enhancing repair of a cartilage and/or inducing formation of a cartilage by administering a cell which expresses a factor of the T-box family, which includes inter-alia the brachyury. In another embodiment, the invention relates to an engineered cell, which is transfected with a vector comprising a nucleic acid sequence encoding a factor of the T-box family, thereby expressing a factor of the T-box family. In another embodiment, the invention relates to compositions comprising a vector which comprises a nucleic acid sequence encoding a factor of the T-box family and in another embodiment the composition comprising cell which expresses a factor of the T-box family, which includes inter-alia the brachyury.