The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2005
Filed:
Jul. 06, 2001
Applicants:
Ian Hector Frazer, St. Lucia, AU;
Xiao Yi Sun, Jindalee, AU;
Inventors:
Ian Hector Frazer, St. Lucia, AU;
Xiao Yi Sun, Jindalee, AU;
Assignee:
The University of Queensland, Queensland, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 510 ; C12N 100 ; C12N 1552 ; C12N 1562 ; C12N 1563 ;
U.S. Cl.
CPC ...
Abstract
A method is disclosed for determining the translational efficiency of an individual codon in a cell. The method comprises introducing into the cell a synthetic construct comprising a reporter polynucleotide fused in frame with a tandem repeat of said individual codon, wherein said reporter polynucleotide encodes a reporter protein, and wherein said synthetic construct is operably linked to a regulatory polynucleotide and measuring expression of said reporter protein in said cell to determine the translational efficiency of said codon.