The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2005
Filed:
Aug. 06, 2001
Joseph R. Woska, Jr., Yorktown Heights, NY (US);
Robert Rothlein, Greensboro, NC (US);
Rene M. Lemieux, Plantsville, CT (US);
Hans C. Reiser, New York, NY (US);
Gary O. Caviness, Danbury, CT (US);
Takashi Kishimoto, Lexington, MA (US);
Kathleen Last-barney, Mamaroneck, NY (US);
Joseph R. Woska, Jr., Yorktown Heights, NY (US);
Robert Rothlein, Greensboro, NC (US);
Rene M. Lemieux, Plantsville, CT (US);
Hans C. Reiser, New York, NY (US);
Gary O. Caviness, Danbury, CT (US);
Takashi Kishimoto, Lexington, MA (US);
Kathleen Last-Barney, Mamaroneck, NY (US);
Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT (US);
Abstract
The present invention relates generally to a method for identifying molecules that bind the R7.1 epitope of LFA-1 or bind LFA-1 such that the R7.1 epitope is modified. The present invention further relates to a method for determining occupancy of the LFA-1 receptor by molecules that bind to the R7.1 epitope or bind LFA-1 such that the R7.1 epitope is modified after administration to a subject. The present invention further relates to molecules useful in the methods of the invention.