The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2005
Filed:
Mar. 15, 2001
Robert A. Copeland, Hockessin, DE (US);
Charles F. Albright, West Chester, PA (US);
Andrew P. Combs, Kennett Square, PA (US);
Randine L. Dowling, Wilmington, DE (US);
Nilsa R. Graciani, Wilmington, DE (US);
Wei Han, Newark, DE (US);
C. Anne Higley, Newark, DE (US);
Pearl S. Huang, Lansdale, PA (US);
Eddy W. Yue, Landenberg, PA (US);
Susan V. Dimeo, Wilmington, DE (US);
Robert A. Copeland, Hockessin, DE (US);
Charles F. Albright, West Chester, PA (US);
Andrew P. Combs, Kennett Square, PA (US);
Randine L. Dowling, Wilmington, DE (US);
Nilsa R. Graciani, Wilmington, DE (US);
Wei Han, Newark, DE (US);
C. Anne Higley, Newark, DE (US);
Pearl S. Huang, Lansdale, PA (US);
Eddy W. Yue, Landenberg, PA (US);
Susan V. DiMeo, Wilmington, DE (US);
Bristol Myers Squibb Pharma Company, Princeton, NJ (US);
Abstract
This invention is directed to antineoplastic agents conjugated to enzyme-cleavable peptides comprising the amino acid recognition sequence of a membrane-bound and/or cell-secreted peptidase, and to the use of such conjugated compounds as chemotherapeutic agents in the targeted treatment of cancers.