The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2005
Filed:
Apr. 10, 2001
Applicants:
David R. Sibley, Gaithersburg, MD (US);
Frederick J. Monsma, Jr., Riehen, CH;
Mark Hamblin, Seattle, WA (US);
Inventors:
David R. Sibley, Gaithersburg, MD (US);
Frederick J. Monsma, Jr., Riehen, CH;
Mark Hamblin, Seattle, WA (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 500 ; C12N 1500 ; C12Q 168 ; C07K 14435 ;
U.S. Cl.
CPC ...
Abstract
Genes encoding the St-B17 serotonin receptor protein were cloned and characterized from a rat striatum mRNA and a human genomic library. The St-B17 receptor has nucleotide and amino acid homology with previously described 5-HT genes and can bind ligands that are known to interact with serotonin receptors. In addition, the levels of intracellular cAMP in cells transfected with the receptor gene respond in a dose dependent manner to introduction of serotonin in the media.