The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2005
Filed:
Apr. 08, 1999
Gene H. Macdonald, Chapel Hill, NC (US);
Brian K. Martin, Durham, NC (US);
Robert E. Johnston, Chapel Hill, NC (US);
Jenny P.-y. Ting, Chapel Hill, NC (US);
Gene H. MacDonald, Chapel Hill, NC (US);
Brian K. Martin, Durham, NC (US);
Robert E. Johnston, Chapel Hill, NC (US);
Jenny P.-Y. Ting, Chapel Hill, NC (US);
University of North Carolina at CHapel Hill, Chapell Hill, NC (US);
Abstract
The present invention provides methods of preventing and/or treating cancers (including tumors). In one preferred embodiment, the invention is practiced to induce regression of an existing cancer or tumor and/or to prevent metastasis and/or to prevent growth of metastatic nodules. In other preferred embodiments, the invention may be used as a prophylaxis to prevent the development of primary cancers through a childhood or adult vaccination program against specific tumor antigens for cancers with high incidences. In an alternate preferred embodiment, the present invention provides methods of establishing an immune response against a universal artificial tumor antigen through a childhood or adult vaccine program, thus providing a long-term immune response that can be utilized at any point to treat any cancer which develops later in life. The present invention also provides cancer and tumor cells stably expressing an artificial antigen, preferably an artificial cell-surface antigen.