The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2005
Filed:
Dec. 04, 2002
Janos Erdei, Debrecen, HU;
Eva Gulyas, Debrecen, HU;
Gabor Balogh, Debrecen, HU;
Laszlo Toth, Balmazujvaros, HU;
Vilmos Keri, Debrecen, HU;
Andrea Csorvasi, Debrecen, HU;
Janos Erdei, Debrecen, HU;
Eva Gulyas, Debrecen, HU;
Gabor Balogh, Debrecen, HU;
Laszlo Toth, Balmazujvaros, HU;
Vilmos Keri, Debrecen, HU;
Andrea Csorvasi, Debrecen, HU;
Biogal Gyogyszergyar Rt., Debrecen, HU;
Abstract
The present invention provides a fermentation process for producing lipstatin comprising the steps of: a) preparing a fermentation medium containing a lipstatin-producing microorganism comprising an oil and an assimilable carbon source, wherein the wt/wt ratio of oil and assimilable carbon source is regulated to achieve an optimal lipstatin biosynthesis by the microorganism; and b) feeding the fermentation medium with an emulsifier, wherein the emulsifier provides an optimal viscosity for the fermentation medium and optimal pH during the fermentation to permit fermentation for lipstatin production. The disclosed process also provides a process for extracting a lipstatin from a fermentation broth.