The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2005

Filed:

Jun. 21, 2001
Applicant:

James Harrison Aylward, St. Lucia, AU;

Inventor:

James Harrison Aylward, St. Lucia, AU;

Assignee:

Peplin Research Pty Ltd, Fortitude Valley, AT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3578 ; A61K 3100 ; A61K 3112 ; A61K 31045 ;
U.S. Cl.
CPC ...
Abstract

This invention relates to a compound or group of compounds present in an active principle derived from plants of speciesand, and to pharmaceutical compositions comprising these compounds. Extracts from these plants have been found to show selective cytotoxicity against several different cancer cell lines. The compounds are useful in effective treatment of cancers, particularly malignant melanomas and squamous cell carcinomas (SCCs). In a preferred embodiment of the invention, the compound is selected from the group consisting of jatrophanes, pepluanes, paralianes and ingenanes, and pharmaceutically-acceptable salts or esters thereof, and more particularly jatrophanes of Conformation II.


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