The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 2005

Filed:

Feb. 04, 1999
Applicants:

Roy A. Black, Seattle, WA (US);

Raymond James Paxton, Bellevue, WA (US);

Wolfram Bode, Gauting, DE;

Klaus Maskos, Holzkirchen, DE;

Carlos Fernandez-catalan, Martinsried-Planegg, DE;

James Ming Chen, Bedminister, NJ (US);

Jeremy Ian Levin, New City, NY (US);

Inventors:

Roy A. Black, Seattle, WA (US);

Raymond James Paxton, Bellevue, WA (US);

Wolfram Bode, Gauting, DE;

Klaus Maskos, Holzkirchen, DE;

Carlos Fernandez-Catalan, Martinsried-Planegg, DE;

James Ming Chen, Bedminister, NJ (US);

Jeremy Ian Levin, New City, NY (US);

Assignees:

Immunex Corporation, Seattle, WA (US);

Max-Planck-Institute for Biochemistry, Klopferspitz, DE;

Wyeth, Madison, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06N 700 ; C12Q 148 ; C12N 910 ;
U.S. Cl.
CPC ...
Abstract

A tumor necrosis factor-α converting enzyme (TACE) is produced, purified, and crystallized. The three-dimensional coordinates of the crystal are obtained by X-ray diffraction. The coordinates can be recorded on a computer readable medium, or are part of a video memory, where they can be used as part of a system for studying for studying TACE. The coordinates are also used in designing, screening, and developing compounds that associate with TACE.


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