The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2005
Filed:
Nov. 26, 2001
Richard H. Hutchings, Ann Arbor, MI (US);
Haripada Khatuya, San Diego, CA (US);
Gee-hong Kuo, Scotch Plains, NJ (US);
Xiaobing LI, San Diego, CA (US);
William V. Murray, Belle Mead, NJ (US);
Catherine Prouty, Doylestown, PA (US);
Frank Villani, Perkasie, PA (US);
Nelson C. F. Yim, Ambler, PA (US);
Cynthia Maryanoff, Forest Grove, PA (US);
Richard H. Hutchings, Ann Arbor, MI (US);
Haripada Khatuya, San Diego, CA (US);
Gee-Hong Kuo, Scotch Plains, NJ (US);
Xiaobing Li, San Diego, CA (US);
William V. Murray, Belle Mead, NJ (US);
Catherine Prouty, Doylestown, PA (US);
Frank Villani, Perkasie, PA (US);
Nelson C. F. Yim, Ambler, PA (US);
Cynthia Maryanoff, Forest Grove, PA (US);
Janseen Pharmaceutica N.V., , BE;
Abstract
This invention relates a to a series of heterocyclic substituted piperazines of Formula Ipharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the α-adrenergic receptor, a receptor which has been implicated in benign prostatic hyperplasia. As such the compounds are potentially useful in the treatment of this disease.