The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 2005

Filed:

Jul. 06, 2001
Applicants:

Stephen H. Bartelmez, Seattle, WA (US);

Patrick L. Iversen, Corvallis, OR (US);

Inventors:

Stephen H. Bartelmez, Seattle, WA (US);

Patrick L. Iversen, Corvallis, OR (US);

Assignee:

AVI BioPharma, Inc., Corvallis, OR (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 2104 ; A61K 4800 ; C12N 1500 ;
U.S. Cl.
CPC ...
Abstract

The invention relates to TGF-β blocking agent-treated HSC compositions and methods comprising the same. The TGF-β blocking agent-treated stem cells are viable for an extended time in culture without replication or differentiation and upon transfer to appropriate conditions are capable of long term hematopoietic reconstitution.


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