The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2005
Filed:
Jun. 12, 2000
Applicants:
David T. Curiel, Birmingham, AL (US);
Bryan Walter Tillman, Birmingham, AL (US);
Inventors:
David T. Curiel, Birmingham, AL (US);
Bryan Walter Tillman, Birmingham, AL (US);
Assignee:
The UAB Research Foundation, Birmingham, AL (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 2170 ; A61K 4800 ; C12N 1574 ; C12N 506 ; C07H 2102 ;
U.S. Cl.
CPC ...
Abstract
The present invention provides a CD40-targeted gene delivery system and a CD40-targeted recombinant adenoviral vector for genetic manipulation of dendritic cells and B cells. Also provided are methods of using this enhanced gene delivery to immune system cells and therefore, enhancing dendritic cell-based immunotherapy.