The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2005
Filed:
Apr. 21, 1999
Phalgun B. Joshi, Vancouver, CA;
Ian C. Mortimer, North Vancouver, CA;
Patrick M. S. Tam, Vancouver, CA;
Ian Maclachlan, Vancouver, CA;
Roger W. Graham, Vancouver, CA;
Phalgun B. Joshi, Vancouver, CA;
Ian C. Mortimer, North Vancouver, CA;
Patrick M. S. Tam, Vancouver, CA;
Ian MacLachlan, Vancouver, CA;
Roger W. Graham, Vancouver, CA;
Protiva Biotherapeutics Inc., Burnaby, CA;
Abstract
The present invention relates to methods for increasing the efficiency of transformation of cycling cells, the methods comprising synchronizing cells at a first stage of the cell cycle, and transforming the cells at a second stage of the cell cycle within about one cell cycle of the first stage with a genetically engineered nucleic acid that encodes a desired gene product. The invention further relates to cancer therapy and, in particular, to methods of efficiently transforming cancer cells with nucleic acids that encode gene products that inhibit the growth of cancer cells.