The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2005
Filed:
Jul. 26, 2001
Gilles Divita, Paris, FR;
May C. Morris, Paris, FR;
Jean Mery, Paris, FR;
Frederic Heitz, Paris, FR;
Joseph Fernandez, Carlsbad, CA (US);
John Archdeacon, Carlsbad, CA (US);
Kyle Horndorp, Carlsbad, CA (US);
Gilles Divita, Paris, FR;
May C. Morris, Paris, FR;
Jean Mery, Paris, FR;
Frederic Heitz, Paris, FR;
Joseph Fernandez, Carlsbad, CA (US);
John Archdeacon, Carlsbad, CA (US);
Kyle Horndorp, Carlsbad, CA (US);
Active Motif, Carlsbad, CA (US);
Centre National de la Recherche Scientifique, Paris Cedex, FR;
Abstract
Peptides that are useful as transfection agents are described. The peptides can facilitate the efficient cellular internalization of a broad range and size of compounds that when non-covalently complexed therewith are efficiently internalized into a cell. Advantages include but are not limited to excellent transfection efficiency, relatively low toxicity, internalization by a broad host cell spectrum, and the simplicity and cost-effectiveness that arise from not having to covalently complex the peptide with a specific molecule to be delivered. Applications include but are not limited to the delivery of diagnostics and therapeutics, as well as drug discovery, gene discovery, and the analysis and/or manipulation of other cellular and molecular biological functions. Claims are made for transfection agents, compositions of matter, including pharmaceutical compositions, reagent kits, methods of delivery, and methods of identification of additional peptides for performing and/or including in the same.